This method could lead to an effective misclassification from BP kinds and you will expose dilution prejudice, perhaps underestimating real contacts

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    This method could lead to an effective misclassification from BP kinds and you will expose dilution prejudice, perhaps underestimating real contacts

    This method could lead to an effective misclassification from BP kinds and you will expose dilution prejudice, perhaps underestimating real contacts

    In the current study, the association of new BP categories with risk of incident CVD was more evident in young adults aged <40 years than in the older subjects, which is in line with earlier studies that also reported a stronger association between BP and CVD outcomes in middle?aged compared with elderly populations. 8 , 46 , 51 , 52 , 53 The reasons for the stronger associations in young adults are unclear.

    The result from BP to your risk of CVD could be toned down having broadening age once the both the frequency out of highest BP and other CVD risk activities in addition to become more prevalent as we age

    In Southern area Korea, new Korean Neighborhood away from Blood pressure computed to utilize the earlier hypertension criteria out of systolic BP/diastolic BP ? mm Hg on account of insufficient clear proof for additional make use of decreasing the blood pressure threshold in order to mm Hg to possess Koreans. 54 , 55 According to the Korean Blood pressure level Fact Sheet 2018, exactly how many anybody identified as having blood pressure levels enhanced off step 3 billion in 2002 to 8.9 billion from inside the 2016, with just 5.seven mil people who have compatible and chronic antihypertensive cures within the 2016. 56 The therapy rate enhanced out-of twenty-two% in the 1998 so you’re able to 59% inside the 2007 and to 61% when you look at the 2016, and also the handle speed improved of 5% into the 1998 to 41% during the 2007 and to 49% in 2016. 56 In the a recent study with the Korean National Health and Nutrients Examination Questionnaire, the fresh incidence away from blood pressure additionally the quantity of adults who are in need of antihypertensive cures would-be enhanced, getting similar with other countries. 55 , 57 , 58 According to present education approaching implementation of the newest guidance during the numerous places, like the You, Asia, and you may Korea, the brand new 2017 ACC/AHA blood pressure levels direction tend to significantly improve prevalence regarding blood circulation pressure and you can what number of patients who need antihypertensive therapy initiation and the ones who need medication intensification international. 57 , 58 , 59 , sixty , 61 , 62 When you look at the research conducted recently throughout the National Health insurance and Diet Test Questionnaire, with respect to the 2017 ACC/AHA guideline, in contrast to the fresh Seventh Shared Federal Panel guideline, new frequency off blood pressure levels has increased off 30.9% so you’re able to forty-five.6%, the brand new portion of You people suitable for antihypertensive treatment has increased out of 34.3% so you’re able to 36.2%, and you will 53.4% people grownups taking antihypertensive medication you desire significantly more intense decrease in the BP. 59 In case there is Asia, use of the 2017 ACC/AHA blood pressure direction would resulted in increment from the incidence from blood circulation pressure out-of twenty five% so you can fifty%. 63 It must be analyzed if for example changes in the symptomatic tolerance and you may therapeutic targets out-of to mm Hg would increase BP control and its related result. Future research is along with had a need to show the brand new connection ranging from BP and you can CVD chance regarding the young population with diverse ethnicity and to determine should your risk/benefit proportion for treatment solutions are good within this low?risk class.

    Age and you will intercourse standardization is actually performed with the direct means on the decades construction of your Korean populace, aged 20 to help you 80 ages, in the year 2010

    The strengths of our study are its cohort study design, the large sample size, the use of carefully standardized clinical procedures, and the almost complete follow?up for CVD events, as the National Health Insurance collects all medical services use covering the entire Korean population. This study also has several limitations. First, as with most previous studies, the determination of BP was based on a single?day measurement, although 3 readings were taken. Second, we did not incorporate changes in ourtime mesajlaÅŸma BP categories and other covariates during follow?up. Third, health behaviors were assessed via a self?administered structured questionnaire used in health checkup programs in Korea, as part of the National Health Insurance plan. Measurement errors in these variables may introduce some degree of residual confounding, similar to most epidemiologic studies. Fourth, we used the Pooled Cohorts Equations in all participants; however, it was not validated in adults aged <40 years. Finally, this is an opportunistic cohort of individuals, who self?presented for the health examination, and hence is not a representative sample of low cardiovascular risk young adults in the community. The study population of this cohort was relatively highly educated, young to middle?aged Korean adults with high accessibility to healthcare resources. We compared our study population with a representative sample of the general Korean population (the Korea National Health and Nutrition Examination Survey). The age? and sex?standardized prevalence of hypertension (defined as systolic BP ?140 mm Hg, diastolic BP ?90 mm Hg, or the use of antihypertensive medication), type 2 diabetes mellitus (defined as fasting serum glucose level ?126 mg/dL or the use of blood glucose–lowering agents), obesity (body mass index ?25 kg/m 2 ), and current smoker was lower than those of the general population (16.6% versus 29.1%, 9.3% versus 10.5%, 27.6% versus 31.5%, and 16.8% versus 26.5%, respectively), indicating that our study population may be healthier than the general Korean population. Thus, our findings might not be generalizable to other ethnic groups or populations with different age, demographic, diet, and health behavior characteristics.

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